Implementation Science

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Open Access Highly Access Research article

Trends in publications regarding evidence-practice gaps: A literature review

Ann E Evensen1*, Rob Sanson-Fisher2, Catherine D'Este2 and Michael Fitzgerald3

Author Affiliations

1 Department of Family Medicine, University of Wisconsin School of Medicine and Public Health, 100 North Nine Mound Road, Verona, Wisconsin, USA

2 Faculty of Health, School of Medicine and Public Health, University of Newcastle, 345 David Maddison Building, Watt and King Streets, Newcastle, Australia

3 Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, Faculty of Health, University of Newcastle, University Drive, Callaghan, Australia

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Implementation Science 2010, 5:11 doi:10.1186/1748-5908-5-11

Published: 3 February 2010

Abstract

Background

Well-designed trials of strategies to improve adherence to clinical practice guidelines are needed to close persistent evidence-practice gaps. We studied how the number of these trials is changing with time, and to what extent physicians are participating in such trials.

Methods

This is a literature-based study of trends in evidence-practice gap publications over 10 years and participation of clinicians in intervention trials to narrow evidence-practice gaps. We chose nine evidence-based guidelines and identified relevant publications in the PubMed database from January 1998 to December 2007. We coded these publications by study type (intervention versus non-intervention studies). We further subdivided intervention studies into those for clinicians and those for patients. Data were analyzed to determine if observed trends were statistically significant.

Results

We identified 1,151 publications that discussed evidence-practice gaps in nine topic areas. There were 169 intervention studies that were designed to improve adherence to well-established clinical guidelines, averaging 1.9 studies per year per topic area. Twenty-eight publications (34%; 95% CI: 24% - 45%) reported interventions intended for clinicians or health systems that met Effective Practice and Organization of Care (EPOC) criteria for adequate design. The median consent rate of physicians asked to participate in these well-designed studies was 60% (95% CI, 25% to 69%).

Conclusions

We evaluated research publications for nine evidence-practice gaps, and identified small numbers of well-designed intervention trials and low rates of physician participation in these trials.