Table 1

The Guideline for the Treatment Resistant Schizophrenia

Step
Treatment
Common Examples

1
FGA #1: 1st trial of a first-generation (conventional) antipsychotic medication
haloperidol (Haldol), perphenazine (Trilafan), fluphenazine (Prolixin), loxapine (Loxitane), molindone (Moban), thiothixene (Navane) trifluoperazine (Stelazine)
2
FGA #2: 2nd trial of a first-generation antipsychotic medication
as above
3
SGA #1: 1st trial of a second-generation (atypical) antipsychotic medication
risperidone (Risperdal), aripiprazole (Abilify), quetiapine (Seroquel), olanzapine (Zyprexa), serlect (Sertindole)
4
SGA #2: 2nd trial of a second-generation antipsychotic medication
as above
5
Clozapine
clozapine (Clozaril) only

Falzer et al. Implementation Science 2008 3:13   doi:10.1186/1748-5908-3-13

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